Determination of total phenols in environmental wastewater by flow-injection analysis with a biamperometric detector

A flow injection (FI) method with a biamperometric detector, based on the biamperometry for an irreversible redox couple, is described for the determination of phenols in environmental wastewater. The method relies on coupling of the oxidation of phenols at one platinum-wire electrode with the reduction of MnO4- at another platinum wire electrode to enable biamperometric detection with an applied potential difference of 0 V. The linear dynamic range for the dependence of current on phenol concentration was from 1.0 x 10(-6) to 1.0 x 10(-4) mol L(-1), with a detection limit of 4.0 x 10(-7) mol L(-1) (signal-to-noise ratio, S/N=3). In comparison with the 4-aminoantipyrine (4-AAP) standard method and the 3-methyl-2-benzothiazoline hydrazone (MBTH) method the proposed method can be used to detect many para-substituted phenols that do not react with 4-AAP and MBTH, and response factors are higher for most of the phenols tested. The method, which is simple, economic, and rapid (180 samples h(-1)), has been applied to the analysis of four wastewater samples. The results obtained were compared with those from 4-AAP method. The recoveries obtained by adding phenol standards to samples ranged from 94.3 to 105.2% with a standard deviation of 3.6%.     

Novel vanadium(V) compounds with a layer structure: synthesis,crystal structures,and solid state NMR spectroscopy of [(VO(2))(2)(4,4'-bpy)(0.5)(4,4'-Hbpy)(XO(4))] x H(2)O (X = P and As)

A novel vanadium(V) phosphate and the arsenate analogue, [(VO(2))(2)(4,4'-bpy)(0.5)(4,4'-Hbpy)(XO(4))].H(2)O (X = P, As; bpy = bipyridine), have been synthesized under hydrothermal conditions and structurally characterized by single-crystal X-ray diffraction. They are the first structurally characterized compounds in the vanadium(V)/4,4'-bpy/phosphate (or arsenate) systems. The two compounds are isostructural and crystallize in the triclinic space group P macro (No. 2) with a = 7.9063(3) A, b = 10.2201(4) A, c = 12.1336(5) A, alpha = 113.4652(7) degrees, beta = 95.7231(7) degrees, gamma = 94.4447(7) degrees, and Z = 2 for the phosphate, and a = 7.8843(6) A, b = 10.3686(7) A, c = 12.2606(9) A, alpha = 113.464(1) degrees, beta = 95.560(1) degrees, gamma = 94.585(1) degrees, and Z = 2 for the arsenate. The structure consists of phosphate-bridged vanadium(V) double chains linked through 4,4'-bpy ligands to form a sheet with the monoprotonated 4,4'-Hbpy(+) ligand being coordinated to the metal atom as a pendent group. The (1)H MAS NMR spectrum exhibits four resonances at 14.2, 9.5, 7.2, and 3.7 ppm with an intensity ratio close to 1:6:6:2, corresponding to three different types of protons in 4,4'-bpy and 4,4'-Hbpy(+) and one type of protons in H(2)O. The peak at 14.2 ppm can be assigned to the proton bonded to the pyridine nitrogen atom, which confirms the presence of 4,4'-Hbpy(+).     

Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme

Mutation of the active-site residue Cys38 of N-Ada converts it from a sacrificial DNA repair protein to an enzyme that uses methanethiol as an external sacrificial reagent to repair DNA methyl phosphotriesters catalytically.     

Stable monovalent aluminum(i) in a reduced phosphomolybdate cluster as an active acid catalyst

Low-valent aluminum Al(i) chemistry has attracted extensive research interest due to its unique chemical and catalytic properties but is limited by its low stability. Herein, a hourglass phosphomolybdate cluster with a metal-center sandwiched by two benzene-like planar subunits and large steric-hindrance is used as a scaffold to stabilize low-valent Al(i) species. Two hybrid structures, (H₃O)₂(H₂bpe)₁₁[Al^III(H₂O)₂]₃{[Al^I(P₄Mo^V₆O₃₁H₆)₂]₃·7H₂O (abbr. Al₆{P₄Mo₆}₆) and (H₃O)₃(H₂bpe)₃[Al^I(P₄Mo^V₆O₃₁H₇)₂]·3.5H₂O (abbr. Al{P₄Mo₆}₂) (bpe = trans-1,2-di-(4-pyridyl)-ethylene) were successfully synthesized with Al(i)-sandwiched polyoxoanionic clusters as the first inorganic-ferrocene analogues of a monovalent group 13 element with dual Lewis and Brønsted acid sites. As dual-acid catalysts, these hourglass structures efficiently catalyze a solvent-free four-component domino reaction to synthesize 1,5-benzodiazepines. This work provides a new strategy to stabilize low-valent Al(i) species using a polyoxometalate scaffold.

Monovalent aluminum(i) species was successfully stabilized using a reduced phosphomolybdate scaffold as a dual-acid catalyst for a four-component domino reaction.

Low- or sub-valence aluminum compounds are increasingly growing into a significant frontier subject in coordination and modern organic synthetic chemistry owing to their unique singlet carbene character, Lewis acid/base properties and catalytic reactivity.¹ However, low-valence aluminum(i) compounds have inherent electron deficiency and exhibit thermodynamic instability, making them prone to self-polymerization with metal–metal bonds² or disproportionation³ to metallic Al and Al(iii) species. Inspired by the special stabilizing effect of metallocene compounds, a ligand stabilization strategy has recently been undertaken to stabilize the low-valence aluminum center.^4,5 In this regard, the utilized ligand should satisfy two key criteria: (i) sufficient steric hindrance is required to inhibit monomer polymerization; and (ii) a suitable electronic effect is needed to stabilize the aluminum(i) center. A few organometallic Al(i) compounds protected by bulky organic groups have been prepared such as [(Cp*Al)₄] (Cp* = C₅Me₅),⁶ and [(CMe₃)₃SiAl₄].⁷ However, despite having the ligand effect, most of these Al(i) compounds still decompose in aqueous solutions or heating conditions. In contrast to organometallic Al(i) compounds, inorganic Al(i) structures, i.e. monomeric monohalides, only exist in gaseous form at high temperature⁸ and to the best of our knowledge, no stable inorganic Al(i) compound is known at room temperature due to thermodynamic instability. Therefore, exploring efficient strategies to synthesize stable inorganic Al(i) compounds remains highly desired but a great challenge.Polyoxometalates (POMs), a diverse family of inorganic molecular clusters based on early-transition metals (W, Mo, V, Nb, and Ta), have extensively attracted attention in research in various fields of materials science, coordination chemistry, medicinal chemistry and catalysis science.^9–11 Owing to their adjustable constituent elements and well-defined structures, POMs have been considered as promising inorganic ligands to stabilize high- and low-valent metal ions. For instance, Rompel et al.¹² reported one Keggin-type [α-CrW₁₂O₄₀]⁵⁻ anion in which a labile {Cr^IIIO₄} tetrahedral unit was assembled at the center of the cluster. Li and co-workers employed a monolacunary Keggin-type inorganic ligand to stabilize a high-valent Cu³⁺ ion.¹³ As a unique member of the POM family, the hourglass-type phosphomolybdate cluster {M[P₄Mo^V₆O₃₁]₂}ⁿ⁻ (abbr. M{P₄Mo₆}₂), consisting of two [P₄Mo^V₆O₃₁]¹²⁻ (abbr. {P₄Mo₆}₂) subunits bridged by one metal (M) center, represents a fully reduced metal-oxo cluster. With all Mo atoms in the oxidation state of (+5), a more negative charge is endowed to the cluster surface.^14,15 Such high electron density of {M[P₄Mo^V₆O₃₁]₂}ⁿ⁻ polyoxoanions provides an electron-rich local environment for the possible stabilization of unusual-valence metals. It is worth noting that the [P₄Mo^V₆O₃₁]¹²⁻ subunit presents near-planar triangular structures with the side sizes ranging from 7.50–7.92 Å (Fig. S1^†). The structural feature can supply sufficient steric hindrance to restrain the polymerization of low-valence metal species. Moreover, the six Mo atoms in each [P₄Mo^V₆O₃₁]¹²⁻ subunit arrange in a planar hexagonal-ring structure like a benzene ring, implying that such {M[P₄Mo^V₆O₃₁]₂}ⁿ⁻ clusters may have a similar delocalized electron structure to conjugated benzene or cyclopentadiene. These features make [P₄Mo^V₆O₃₁]¹²⁻ a promising candidate with respect to organic protecting groups to construct an inorganic ‘ferrocene’ analogue of Al(i) (Scheme 1). Therefore, we hypothesize that hourglass-type polyoxoanion clusters are promising to stabilize the labile Al(i) center and isolate inorganic Al(i) species.Open in a separate windowScheme 1Similar ferrocene-like sandwich structure features of an inorganic hourglass-type [Al^I(P₄Mo^V₆O₃₁)₂]²³⁻ polyanion to an organometallic [(η⁵-Cp*)₂Al^I]⁺ cation.Herein, we show a [P₄Mo^V₆O₃₁]¹²⁻ cluster as an inorganic scaffold to stabilize the Al(i) center in two hybrid compounds, (H₃O)₂(H₂bpe)₁₁[Al^III(H₂O)₂]₃{[Al^I(P₄Mo^V₆O₃₁H₆)₂]₃·7H₂O (abbr. Al₆{P₄Mo₆}₆) and (H₃O)₃(H₂bpe)₃[Al^I(P₄Mo^V₆O₃₁H₇)₂]·3.5H₂O (abbr. Al{P₄Mo₆}₂) (bpe = trans-1,2-di-(4-pyridyl)-ethylene), in which the labile Al(i) center is sandwiched by two [P₄Mo^V₆O₃₁]¹²⁻ sides, forming an inorganic moiety of a ‘ferrocene’ analogue. Both Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ are experimentally determined at room temperature for the first time, and prepared by hydrothermal reactions of Na₂MoO₄·2H₂O, H₃PO₄, AlCl₃·6H₂O, ethanol and N-containing bpe at 160 °C with slightly different pH values. Notably, the combination of ethanol, N-containing bpe and high hydrothermal temperature is a prerequisite to the isolation of Al(i) species. First, both ethanol and N-containing bpe were used to provide a reducing environment under hydrothermal conditions. By combining high temperature and pressure, sufficient energy is supplied to reduce Mo⁶⁺ and Al³⁺ ions to Mo⁵⁺ and Al⁺ species, respectively. Then, Mo⁵⁺ species and phosphoric acid molecules are assembled to form [P₄Mo₆O₃₁]¹²⁻ subunits, which are subsequently combined with Al⁺ ions to form hourglass-type [Al(P₄Mo₆O₃₁)₂]²³⁻, hence effectively stabilizing Al(i) species (Fig. 1). From the perspective of stereochemistry, two highly negative [P₄Mo₆O₃₁]¹²⁻ fragments, resembling the methyl cyclopentadiene organic group, sandwich one low-valent metal Al(i) center. Hence, the construction of a strong reducing hourglass-like skeleton makes it possible to stabilize the existing Al⁺ species.Open in a separate windowFig. 1Ball-and-stick diagram showing the assembly of the hourglass-type cluster {Al(P₄Mo₆)₂}.Single crystal X-ray diffraction revealed the hourglass-type {Al(P₄Mo₆)₂} cluster in Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ (Table S1^†), in which the [P₄Mo₆O₃₁]¹²⁻ subunits have a C₃ symmetry and display a near-planar structure formed by six edge-sharing {MoO₆} octahedra with alternating short Mo–Mo single bonds and long non-bonding Mo⋯Mo contacts. The side sizes of the {P₄Mo₆} subunit range from 7.50–7.92 Å, which supplies sufficient steric hindrance to restrain the polymerization or disproportionation of low-valence Al(i) species. All Mo atoms are in a reduced oxidation state of +5 and the central Al atoms are in the +1 oxidation state, as confirmed by bond valence calculations (Table S2^†). Thus, the synthesized Al{P₄Mo₆}₂ represents a fully reduced metal–oxygen cluster. Moreover, the six Mo atoms in each {P₄Mo₆} subunit present a benzene-like planar hexagonal-ring structure with a similar π-type delocalization electron interaction with Al(i) instead of organic bulky groups. Such π-type delocalization electron interaction constructs an inorganic ‘ferrocene’ analogue of Al(i) and produces sufficient delocalization energy to stabilize Al(i) species. Considering the formation mechanism of traditional metallocenes, {P₄Mo₆} subunits with a similar strong electron-donating ability and suitable steric-hindrance effect on Cp rings, augment the stability of Al(i) species. Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ compounds also present the first isolation of aluminum-sandwiched hourglass-type clusters in POM chemistry. Importantly, regarding the inherent and strong hydrolysis of aluminum species in water, these low-valent Al(i)-containing clusters represent the first example of stable solid-state inorganic sub-valent Al(i) compounds at room temperature.The asymmetric structure of Al₆{P₄Mo₆}₆ consists of two crystallographically independent {Al(P₄Mo₆)₂} clusters sandwiched by central Al(1) and Al(4) atoms, two bridging [Al(H₂O)₂]³⁺ (Al(2) and Al(3)) cations and six protonated bpe cations (Fig. S2^†). Aluminum centers involve two kinds of oxidation states: the central Al(1) and Al(4) are in the +1 state, while the bridging Al(2) and Al(3) are in the +3 state. Both Al(1) and Al(4) display the six-coordinated octahedral configuration and bridge two {P₄Mo₆} subunits to form two {Al^I(P₄Mo₆)₂} clusters. The average lengths of Al–O bonds are 2.318–2.324 Å for Al(1) and Al(4) (Table S3^†), which are slightly longer than those of classic Al–O bonds (1.90 Å) for Al(2) and Al(3), but close to that of the Al–O bond in silica-supported alkylaluminum(i) composites.^16–20 The long Al–O lengths for Al(1) and Al(4) centers may be ascribed to the lower electron cloud density located at the surface of the Al(i) cation, resulting in slightly longer bonds with the surrounding oxygen donors.^5,21 Moreover, the small distorted extents (sum((d_ij − d_ave)/d_ave)²/coordination number) of {Al(1)O₆} (3.86 × 10⁻⁴) and {Al(4)O₆} (1.89 × 10⁻³) indicate that they are in regular octahedral geometry. Moreover, another structural feature of Al₆{P₄Mo₆}₆ is that {Al^I(P₄Mo₆)₂} clusters are connected by bridging [Al(H₂O)₂]³⁺ cationic fragments (Al(2) and Al(3)), forming an unusual chain-like arrangement (Fig. 2a). It is worth noting that the 1-D chain contains a large repeating monomer with the maximum spacing of 81.69 Å, consisting of twelve Al-containing fragments ({–Al2–Al1–Al3–Al4–Al3–Al1–Al2–Al1–Al3–Al4–Al3–Al1–}). Such a long repeating monomer is rare. Each repeating monomer has two types of symmetric systems: Al(2) in the middle of the monomer plays a center of mirror symmetry and divides the whole repeating monomer into two equidistant half-units of {–Al1–Al3–Al4–Al3–Al1–}; Al(4) in each half-unit further acts as the reverse symmetric center of two {–Al3–Al1–Al2–} subunits. The two types of symmetrical systems form the infinitely extending chain-like structure in Al₆{P₄Mo₆}₆. Since bpe is a rigid and conjugated molecular structure, an effective π⋯π stacking interaction emerges and results in a honeycomb-like supramolecular organic moiety, which accommodates these 1-D inorganic chains and stabilizes the whole Al₆{P₄Mo₆}₆ framework (Fig. S3 and S4^†).Open in a separate windowFig. 2(a) One-dimensional (1D) inorganic structure in Al₆{P₄Mo₆}₆ with a length of repeating units of 81.69 Å, consisting of twelve Al-containing fragments ({–Al2–Al1–Al3–Al4–Al3–Al1–Al2–Al1–Al3–Al4–Al3–Al1–}). (b) Four kinds of coordination environments of {AlO₆} octahedra, respectively (i = 1 − x, y, 0.5 − z; ii = 0.5 − x, 1.5 − y, 1 − z).Al{P₄Mo₆}₂ has a similar structure to Al₆{P₄Mo₆}₆ (Table S4^†), wherein the most obvious difference is that {Al^I[P₄Mo₆]₂} clusters exist in isolated form and interact with the surrounding protonated bpe cations via hydrogen bonding to form into a 3-D supramolecular framework (Fig. S5 and S6^†). The different peripheral environment around the {Al^I[P₄Mo₆]₂} cluster can affect its acidity and catalytic activity.The solid-state ²⁷Al NMR spectrum of Al₆{P₄Mo₆}₆ depicts two distinct resonances at δ = −22.34 and 27.33 ppm due to the octahedrally coordinated Al^III and Al^I sites, respectively (Fig. 3a), indicating two types of Al local environments in Al₆{P₄Mo₆}₆. In contrast, Al{P₄Mo₆}₂ displays only one sharp signal at δ = 7.20 ppm due to the octahedrally coordinated Al^I sites (Fig. 3b). The observed narrow peak-width corresponds to the highly symmetric charge distribution at the aluminum nucleus, similar to the ferrocene analogue [(η⁵-Cp*)₂Al^I]⁺.⁵ Noticeably, Al^I resonance in Al₆{P₄Mo₆}₆ appears at a lower magnetic field compared to Al{P₄Mo₆}₂, due to the different peripheral environment around the hourglass {Al(P₄Mo₆)₂} cluster. XPS spectra of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ further affirm the valence states of Al and Mo elements (Fig. S7 and Table S5^†). The Al 2p XPS profile of Al₆{P₄Mo₆}₆ reveals two peaks at 74.39 and 73.75 eV ascribed to Al^III and Al^I, respectively (Fig. 3c). The area ratio of the two peaks is close to 1 : 1, in consistence with the chemical structure of Al₆{P₄Mo₆}₆. The high-resolution Al 2p XPS spectrum of Al{P₄Mo₆}₂ displays a weaker broad peak attributed to the low amount of Al⁺ (Fig. 3d). Moreover, the structural stabilities of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ were investigated by soaking them in water for 24 hours. Fig. S9–S11^† show the comparison of XRD, IR and XPS spectra of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ before and after soaking in water. It can be found that the characteristic diffraction peaks in XRD after soaking for 24 hours still show good agreement with the simulated data (Fig. S9^†). The characterized absorption bands in IR spectra also exhibit good match with the original Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ (Fig. S10^†). The XPS spectra of Al₆{P₄Mo₆}₆ after soaking in water were also obtained. There is basically no change in the high-resolution spectra of Al 2p with the Al^I/Al^III atomic ratios of ca. 1 : 1 (Fig. S11^†). The spectroscopic and theoretical observations verify that the low valence Al(i) species can stably exist in the reduced phosphomolybdates in the solid state (Fig. S12 and Table S6^†). Moreover, the acidities of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ were measured to be 0.27 and 0.442 mmol g⁻¹, respectively, demonstrating the promising potential of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ as dual-acid catalysts.Open in a separate windowFig. 3(a and b) ²⁷Al NMR spectra of solid Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂; (c and d) XPS spectra of Al in Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂.The catalytic performance of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ was evaluated via a solvent-free four-component domino reaction for the synthesis of pharmaceutical intermediate 1,5-benzodiazepine (Table 1). With Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ as catalysts, the yields of the final product 8aaa reach 83% and 75%, respectively (Table 1, entries 1 and 2). Almost no 8aaa is observed without the acid catalysts, even when the reaction is set for a long time (Table 1, entry 3). This clarifies the excellent catalytic performance of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂. Typical Brønsted acid p-TsOH and Lewis acid AlCl₃ as control samples yield only 43% and 29% 8aaa, respectively (Table 1, entries 4 and 5), much lower than those attained by Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂ catalysts. Moreover, (H₂en)₁₂[{Na_0.8K_0.2(H₂O)}₂{Na[Mo₆O₁₂(OH)₃(HPO₄)₂(PO₄)₂]₂}₂]·7H₂O^22,23 (abbr. {Na[P₄Mo₆]₂}) in contrast achieved 72% yield of 8aaa in 30 min, slower than that of Al₆{P₄Mo₆}₆ and Al{P₄Mo₆}₂. This indicates the advantage of the unique dual-acid features of Al(i)-stabilized reduced phosphomolybdate clusters with multiple Lewis and Brønsted acid active centers, in which the synergistic effect between the Al species and reduced phosphomolybdate cluster contributes to the catalytic activity.Comparison tests of one-pot synthesis of 1,5-benzodiazepine 8aaavia a four-component domino reaction^a

An indium(III)–water chain based on an unusual acyclic water pentamer

An in situ reaction under hydro­thermal conditions leads to the formation of the title compound, diaqua­(pyridine‐2‐carboxyl­ato)­(pyridine‐2,6‐dicarboxyl­ato)indium(II) trihydrate, [In(C₆H₄NO₂)(C₇H₃NO₄)(H₂O)₂]·3H₂O, in which the central In^III atom is seven‐coordinated by one pyridine‐2,6‐di­carboxyl­ate ligand, one pyridine‐2‐carboxyl­ate ligand and two water mol­ecules in a penta­gonal–bipyramidal coordination environment. An indium(III)–water chain based on an unusual water pentamer is observed.     

The Synthesis of Gracillin and Dioscin：TWO Typical Representatives of Spirostanol Glycosides

Two spirostanol saponins(gracillin and dioscin)which have the typical sugar moieties were synthesized facilely by a general approach.     

茶叶中咖啡因的纸基质室温燐光法体内药代动力学研究

以快速定量滤纸为基质 ,用KI NaAc为重原子微扰剂建立了测定痕量咖啡因的滤纸基质室温光(PS RTP)分析法。并用于茶叶中咖啡因的测定及其在人体内的药代动力学研究。实验表明 :PS RTP法用于茶叶中咖啡因的测定准确、灵敏。受试者饮茶后 1～ 2h尿样中咖啡因排泄达高峰 ,2 4h后基本排泄完毕。咖啡因的尿排泄量占总摄取量的 64 .2 5 %。     

Polarographic Behaviour and Determination of Kinetic Parameters of Lead-Pamoate Complex in Dimethyl Sulfoxide

The polarography of lead ion in dimethyl sulfoxide (DMSO) was investigated in the DMSO concentration range 0–80 vol.%. The complex species identified were Pb₂(DMSO)⁴⁺₃, Pb(DMSO)²⁺₃ and Pb(DMSO)²⁺₆ in [DMSO]<10 vol.%, 10< [DMSO]<43 vol.% and [DMSO]>43 vol.%, respectively. In the presence of pamoic acid, the reduction of lead ion in DMSO was two-electron reversible diffusion-controlled at pH≤6.0, but it became irreversible at pH>6.0. The complex species identified was Pb(D_m)₂(P_m)₃(OH)^6? at pH>6.0. The rate constants of electro-reduction and electro-oxidation, activation energies were determined. The hydrolysis constants of lead ion in dimethyl sulfoxide concentration 40–70 vol.% at pH 4.5–6.0 were found to be of the order of 10^?6. The stability constants of the Pb(DMSO)²⁺₃ and Pb(DMSO)²⁺₀ were also determined to be of the orders of 10¹ and 10⁵, respectively.     

Preparation and Superconductivity of a Series of Bi2CaSr2-XBaxCu2O8+δ

By means of the addition of Ba into the Bi-Ca-Sr-Cu-O 2122 system, a series of Bi₂CaSr_2-xBa_xCu₂O_8+δ (0 ≤ × ≤ 2) quinary metal oxides were prepared by the citrate route and by the conventional powder reaction method. The samples prepared by the former method have better properties than the latter. It was found that 5 was not equal to zero for all of them and that it increased with decreasing Tc. Two phases were indentified in the oxides containing all five metal elements. One is the Bi-Ca-Sr-Cu-O 2122 phase, the other is a new insulating phase which probably contains Bi-Ca-Ba-Cu-O with undetermined stoichiometry. Superconductivity was found in those samples for which × ≤ 1.50 with their Tc onsets between 93–78 K by resistivity measurements. Superconductivity decreased monotonically with increasing x. However, residual resistance was found in those samples for which 1.00 ≤ × ≤ 1.50, The Meissner effect appears in the samples where × ≤ 1.00 with Tc onsets between 88–80 K. For x = 1.75 and 2.00, the samples were semiconductors with resistivities of 6.66 × 10² and 6.96 × 10³ Ω cm at 290 K, and activation energies of 0.109, and 0.298 eV, respectively.